This course is a 1 unit optional laboratory counterpart to “Genomics” (HMGP 7620) offered in the School of Medicine at UC Denver for Spring 2011.  The objective of this unit will be to give students with little programming or Linux/UNIX proficiency enough background and hands-on experience to be able to: write simple Perl scripts to obtain, reformat, and process large genomic data sets, to work with large short-read ‘next generation’ DNA sequence data files, to perform basic data manipulation including sequence alignment, mapping, assembly, and homology-based search, and to introduce methods and software for extracting meaningful information from pattens of intra- and inter-specific genomic variation using phylogenetic methods, simulation, and advanced statistical techniques.

Note: This is a hands-on ‘boot camp’ style course that involves weekly readings and assignments.